Immune Disorders

Common Variable Immunodeficiency (CVID) is a primary immunodeficiency disorder characterized by impaired antibody production, leading to a weakened immune system. People with CVID have reduced levels of immunoglobulins (antibodies) in their blood, making them more susceptible to recurrent infections, particularly in the respiratory system, such as sinusitis, bronchitis, and pneumonia.

CVID typically manifests in late childhood or adulthood, and the exact cause is often unknown, although genetic factors are believed to play a role in some cases. Individuals with CVID experience a wide range of symptoms and disease manifestations. Besides recurrent infections, they may also have autoimmune disorders, such as rheumatoid arthritis or lupus, and an increased risk of developing certain types of cancer. The severity and frequency of infections can vary among individuals, and some may require regular infusions of immunoglobulin therapy to boost their immune system and prevent infections.

Treatment for CVID focuses on managing infections through antibiotics, prophylactic medications, and immunoglobulin replacement therapy. Regular monitoring and close collaboration with healthcare professionals, including immunologists and infectious disease specialists, are crucial for effectively managing CVID and optimizing the quality of life for individuals with this condition.